If you go there alone in power armor, nobody attacks you unless you attack them. The enclave, while not as content-rich as some of the other towns, does have some pretty major plot points you can uncover and has a few different ways to go about things. You could go through the whole thing and pass with flying colors without firing a single shot.[spoiler:a156236de9] You can even defeat horrigan, the "end boss," without weapons by having the team by the doors join you and by using the presidential pass(obviously obtained from the president) on the terminal in the south west corner.[/spoiler:a156236de9]
To battle them, make sure you have a good weapon(gauss gun, plasma rifle, or, if you're handy with small guns, revolver shots to the eyes) A set of power armor(which you should already have if you are at the enclave) at least eight action points, and maybe a few party members with similarly strong weapons and armor.