I don't like how the only use for Science I've ever found is using computers. I liked how they turned Repair into a necessary skill to have (in the first games, repair was largely unecessary due to books, specially with Vic nearby), and those that invested their skill points in repair will find themselves with very powerful weapons and armor in the endgame. Also, repair is excellent to eliminate some of the fodder loot.
Science is only for computers, or so it seems. Sure, in Fallout 2, it was used by computers, but they had far more uses. With Science, you could:
Make a lot of things with computers. Hack systems, disable and enable forcefields, disable traps and read logs.
Recruit Skynet (specially good for evil chars)
Talk about Jet with Myron and even make the jet antidote by talking to Dr. Troy about Jet.
Find out how to take out the reactor computer or find out about FEV-Curling in the Oil Rig.
You can make the robot fix the Gecko Reactor for you.
You can contact the Enclave for pure lulz and a ambush if you're playing mods with it, like RP or MIB888.
(Restoration Project) You can activate the Turrets without the keycard using high-enough science skills.
(Restoration Project) You can do a lot of things in EPA, like making chems and using computers.