The original games made relatively little use of radiation. Fallout 3 makes it more of an issue (one of it's saving graces).
DC would be heavily targeted. I'd be surprised if it looked as good as it does in Fallout 3.
Back on the west coast, depending on how similar the Fallout world is to ours, an arc running from north of LA south and east to San Diego would probably be hit hard (aerospace and other defense industry in the desert, Navy stuff on the coast). East of San Francisco, there was Alameda Naval Air Station, Concord Naval Weapons Depot (with nukes), Lawrence Livermore Labs, Tracy Weapons Depot, Beale Air Force Base (Strategic Air Command bombers)... So there should still be lts of radiation in the FO1 and FO2 areas.
An interesting real-world guide is the US Federal Emergency Management Agency's "
Nuclear Attack Planning Base 1990". Look at Annex A, "Direct Effects..." to see where bombs fall, then at Annex B, "Fallout Risk..." You will see that fallout mostly travels west-to-east.
Oh, and the midwest is amazingly f-ed. All those silos demanded a lot of groundburst hits.
This was a model of a Soviet attack done in the mid-80's. It assumes casualties and damage that must be very low compared to Fallout's Great War, which must have used a lot more warheads and bigger yields.