Black Angel
Grand Inquisitor of the Ordo Hereticus
Eh, I'd say "global scale" is actually present in Fallout 1 far more than Fallout 2. Just like you said, every single town in Fallout 2 is indeed so different from one another. However, only the ones that's in direct vicinity of the Golden Trail (of NCR-New Reno-Vault City with Redding in the 'center) that actually have any meaningful interaction between each other. Places like Arroyo (starting point), Klamath (narrative hook from starting point), The Den (continuation of narrative hook), Modoc (stumble upon it on the way to Vault City, kinda like Shady Sands), and obviously San Francisco (as the endgame point) are actually detached from the rest of the Golden Trail. I guess you can cut The Den some slack since it has connection with New Reno (Frankie buying his alcohol from there, and Metzger's biggest buyer is the Mordinos iirc). Aside from San Fran, the second most jarring place of Fallout 2, in my opinion, is Modoc. While the game explicitly shown that there's indeed trading going on between Modoc and the rest of the region, for some reason it doesn't seem to be connected with the Golden Trail. It's weird that with RP, we have a quest to help that Vault Village establish trading with caravans, but no such quest is present in Modoc.Every single town is so different from another, and yet, they interact with each other in a believable way (the whole plot centered around the Bishops, Vault City and the NCR is actually very interesting. It has that "global scale" that is missing from Fallout 1.)
Meanwhile, in Fallout 1, literally ALL settlement is connected by trading, with The Hub acting as literal hub between the towns. Even Necropolis is included in the trading circle. Only Shady Sands for some reason not involved in this, though I guess you can say it's due to the Khans having a base between it and The Hub, and even then you can actually find a random encounter with a caravan group heading for Shady Sands.
Also, not to mention second-phase time limit of Fallout 1, where the Super Mutants will invade ALL settlement on the map should the Vault Dweller lollygag for far too long, I wouldn't say the sense of "global scale" is missing, or even lacking at all in Fallout 1.