SCIENCE! in Fallout: How, why, good, bad? Yeah, good idea. I generally agree. I have no problems with the Holograms though. It definitely is imo. The FEV itself is something that is already extremely ridiculous when you think of it and basically impossible to create (essence of SCIENCE!). I'm not a fan of the wild FEV + radiation created mutated wildlife theory by the way. I prefer radiation only and FEV being responsible for the more gruesome mutations (as developed by MCA in the last Fallout bible). Now modifying that already extremely complicated virus into something that perverts it's purpose into eradicating only the human genome is certainly a 'great' achievement. The respective serum might not seem like much coming from that, but it is. The resources weren't necessarily that abundant in accessibility (they enslaved 'mutants' and dealt with mainlanders) and the Enclave was just as isolated as Big MT (which brings us to the question of possible other Enclave bases which I don't believe in, since I don't like that approach. There are outposts in Chicago which were installed after the migration of Autumn senior's chapter, let's drop any other possibilities). Harkness was the epitome of the Institute's anvancement. There definitely were links between purely anorganic human-like robots to partly organic synthetic humans. There are definitely things that I'd like to see confirmed. Let me testify some things: Harkness can not reproduce, he can shit, he can fuck, bleed and even heal wounds automatically (anything else would have made him question his humanness). He's immune to mutation. He doesn't age. He's immune to sickness, which would have definitely brought up some questions in the future. How and why create something like that? First, MIT was a prime actor of robotics. One of their graduates was the founder of RobCo and revolutionized the world. They definitely did further research and development post-war. I hope they developed from a mens et manus mentality into a 1984 like enclosed society with an overbearing ideology that mystified idols like Mr House. The foundation of AIs was laid before the war already. As to thew how. The why lies in darkness. I assume that they wanted to overcome human fragility without sacrificing human needs and wants. A Robobrain or something like the Think Tank transcends humanity into a state our brain isn't capable of withstanding without (at least psychological) damage. A body that doesn't age, die or succumb to illness, yet at the same time preserves our humanity is a goal that's worth to strive for. Testing these bodies with artificial brains first leads to implementing true human ones later.