Well, actually it might have been kind of nice to include some psyker antagonists, like f.e. a decrepit crazy guy squatting in some fine lootable building, looking like Snork from S.T.A.L.K.E.R. or something, who can be easily beaten with bare hands, but who, when approached without Psychic Nullifier (which is sold by some wandering scrap merchant under an innocuous name) will lock you into a nightmarish scene (endless corridors, household objects looking like body parts, sludge coming out of walls or hopefully something less banal) with epilepsy-inducing lights and screen vibrating and sickening amounts of motion blur, with the only way to exit being Alt+F4.
Oh, and the last savefile would get corrupted as well.
That would be a very nice joke, I think.
Psykers for protagonist are a no-go, of course.