I'm going to go against the grain here for a moment and suggest that Emil was perhaps being somewhat transparent. If he was being honest he would have really said: "The general audience I'm delivering this story to is to stupid to comprehend anything beyond 'find daddy; save day - goo goo gah gah'"
I have questioned whether the removal of some mechanics from Fallout 4 and the butchering of the dialogue system were done intentionally, to appeal to less intelligent audiences. However, the more I learn about how Bethesda design games these days, the more convinced I become that the failures of Fallout 4 were not some dark conspiracy or a savvy marketing move by Bethesda to maximize profits.
They were simply the result of their incompetence and pride.
This conference only contributes to my opinion. Neither Emil, nor Todd Howard sound like con men to me. Sure, they have become very good at presenting their games, (I know, tell me lies) but one thing I have noticed is that they always seem proud of the work that is being done at Bethesda.
On many occasions, Todd Howard has stated that they never make the same game twice. Statements like these are supposed to convince us that BGS is always striving for innovation and is never content with the status quo. In reality, however, Bethesda have become so obsessed with reinventing the wheel that they have begun to forget what made their own games good in the first place. (The example I gave earlier about contradiction between player action and player character) There is no "innovation" in their most recent games. There is a change of design direction. Every positive change seems to come at the cost of two negative.
They were never interested in providing us with a spiritual successor to the original games or even learning from the real innovations done by Obsidian. With Fallout 4 they wanted to make their own game set in the universe. They kind of tried to refer to the originals with Fallout 3, but mostly failed because... well, Pagliarulo... Yet, people condemned that game and didn't even give them credit for trying. So, 8 years later, a much better known Bethesda with huge profit from their previous game decide that they can get away with doing their own thing. Why are people so surprised? Suggesting that the whole project was a secret experiment to appeal to dumb people.
Sadly, the fact is that Fallout 4 is probably now the game in the franchise played by the most people. People would have played it regardless of whether the writing was any good or not, because it came after Skyrim, had an incredible marketing campaign, was announced at just the right time, generated incredible amounts of hype, etc. I can see why Bethesda might have focused more on the shooter aspects in Fallout 4 (I mean, just look at the trailer... What do you see? Shooting, guns, building, silly costumes. Of course it was marketed to those people), but make the writing intentionally dull and simple? Don't think so. That one was on pure and simple incompetence.