How is Fallout 4 even possible, if cryogenic tech KILLS YOU IN FALLOUT!?

I didn't say there wasn't any experiements, but fallout 2 literally starts with a vault opening and the people waving happily as if their lives were perfect...Before being eradicated by the Enclave.
Don't forget that Vault 12s experiment was to actively irradiate the participants.

Just because one vault's denziens were treated well, doesn't mean all of them are.
 
I have no doubt that the people at Bethesda have played F1 and F2, simply because of how many plot elements they've needlessly rehashed in their games. If only they took more spiritual and thematic influences from them instead of specific story beats and characters/factions.

As for what happened to Dobbs, it was a different procedure using different technology, and it's entirely possible that something might have gone wrong in the process of preserving him. I think there's wiggle room there, although it would have been nice if Bethesda had at least acknowledged the existence of post-cryogenic syndrome, maybe in a terminal entry talking about how they managed to avert that issue in Vault 111.
 
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