Alesia Connor, 1st Recon (former) then courier. The story is long and actually I have a fanfic in the works about this character because she was one of my favorite trips through the game.
Been playing as Duke for awhile now, partly for my Duke Nukem: Lost in New Vegas Lets Play, and partly because it's so much fun. Duke doesn't take shit from anyone in the Mojave and his companions are the same way. Check out the threads if it pleases ya.
Focused in Unarmed and Melee with their associated perks and learned just about all the unarmed special moves excluding the technique taught by the Great Khan since I took out Vault 3's inhabitants before realizing I need to complete the quest first.
Fallout 3's last character I played with trying to complete 100% all trophies and everything else I hadn't touched up on completely.
Mr. House's Associate
Focused in Energy Weapons primarily with a balance in other skills required to make it through the Mojave.
NCR/BoS/Enclave Associate
This one is the high INT and extremely Lucky player, I wanted to get the casino and Caravan related trophies so I went with the Blackjack route and in around 20 minutes each, I was kicked out of the casino and got my goal. Right now I'm rapping up loose ends and will be getting the best Raul ending as well.