Some vaults were pretty much made to die (Vault 12, Vault 106), while some were made to stay isolated for a long time (Vault 13 and Vault 101, except that Vault 13 was supposed to stay locked for 200 years, while Vault 101, I don't know... It was supposed to be locked forever or at least until the Enclave needs them, right?) and some were hit-or-miss (Vault 15, 27, 29, 42, 53). I can't believe all vaults in the capital wastelands were made to die horribly, that would be kinda crazy.
EDIT: Another hole in Fallout 3 is about Megaton and Vault 101. Lemme see... So, we have Megaton, a city full of people armed with guns and they surely have acess to explosives. And then we have Vault 101, a place whose security staff is possibly small, only has stupid 10mm pistols and they can barely fight off some stupid rad-roaches. Heck, I myself teared the security team appart. Alone, with a 10mm pistol.
So the people of Megaton live in a wasteland shit hole near a nuclear bomb while the people of Vault 101 live with technology, comfort and acess to food and water undreamed by any wastelander outside the Brotherhood or Enclave. Vault 101 is about ten minutes of walking from Megaton. They KNOW the Vault exists, the vault has contacted them before. Can someone explain me WHY the dwellers of Megaton never tried to blow the door and take the vault for themselves? The people of Megaton have to drink water from a shitty, old purifier. The people of Vault 101 have a water chip. They don't got a GECK, but fuck that, even without a GECK, with proper ammounts of water, they could've all the food they want. Why Vault 101 was never invaded?! Sure, there are those raiders trying to dig in, but why should they waste their time digging instead of buying a shitload of bombs and blowing that door?