Fallout: New Vegas is the only game I'm looking forward to this year. But, truth be told, I don't really play many games as of recently and haven't been following any gaming news (except news from NMA).
So, why wouldn't New Vegas be among the "Most Anticipated"? I recall that Fallout 3 did quite well in the market, gained a lot of recognition to the Fallout franchise, and picked up quite a good number of new fans that love Fallout 3. Why wouldn't a new game be anticipated, especially one so much like the commercial success that was/is Fallout 3.