Megaton is a shanty town built around an unexploded nuclear bomb. Nobody before seemed to realize "holy shit that is a terrible idea you guys, we should run away!", nope, let's just build our town around a source of deadly radiation that could go off at any moment and kill everyone. Tenpenny Tower is a gigantic hotel suite in the middle of fucking nowhere. It services "rich" people. Why are they rich? Considering that nobody in the wasteland produces anything, including food, clothing, any sort of manufactured goods, and indeed, does not even seem to have a real functioning economy, it makes absolutely no sense for there to be any "rich" people at all. Who maintains this hotel? How do they get supplies out in the middle of nowhere? Rivet City makes the most sense because as an abandoned aircraft carrier it's an easily defensible location. Even so, there is absolutely nothing interesting that happens there - it's full of boring NPCs and the quests there involve trying to stop an old man from committing suicide, and helping a young woman rape a man and then guilt trip him into marrying her. Brilliant. No, it's a bad idea period. Why is purifying the water of the wasteland so important when everyone seems to be able to get along just fine? Has anyone tried using rainwater instead of toilet water? There seems to be tons of 200-year-old food everywhere to eat so why would anyone bother with agriculture, which is the only reason one can really justify the need for purified water? If you wanted to purify the water of the entire wasteland then why in the name of fuck would you build your purifier in a river basin? Wouldn't building portable personal-sized purifiers be more convenient than shipping water out throughout the entire wasteland? Didn't daddy Neeson just say that he got the purification technology working on a small scale, so he could already do this if he wasn't a fucking moron? Do you see now how this shit is stupid beyond belief and completely contradicts the core details of the setting and universe that Bethesda themselves established?