As long as this thread is around I might as well contribute to its longevity.
Fallout: Super Sledge (Fast Shot and Bonus H+H attacks= 1 AP for attack, 10 swings a round, very cheap, but it kills all), Combat Knife, 14mm Pistol, Mauser, Flamer (best for evil characters).
Fallout 2: Wakazashi, unarmed, FN FAL, Needler, Mauser.
Fallout Tactics: Scalpel, Sten Gun, Ripper, Needler, FN FAL, Mauser.
Up close, and most of the time, personal. (except for the FN FAL and Sten)
Gauss is fun, but it is cheap as hell. I managed to get 3000+ rounds in my inventory, WITHOUT cheating.
Bozar, never bothered.
How do you get a uranium nugget? I swear, I start the game over and I find something entirely new. (Have yet to be a made man for Sal or Bishop, just an example of my goody-two shoeness)