Fantastic stuff, I've told whoever would listen for years that Fallout 2 had enough unfinished/intended things left over to damn near warrant a whole new release, and you made it reality.
Played through Arroyo, Klamath, the Den, and at the Primitive Tribe right now. In regards to what was said before, about the fight at Tyler's party, in general, it all works fine, but what might be the problem is that Tyler's friend (great attention to detail by the way, including the friend he mentions) runs off the moment the fight starts, and Lara won't consider it finished until he's dead. He just keeps running, so it's kind of a pain, but I got lucky (he tried running into the Orphanage....I actually felt alarmed at that for a minute, "My god, the kids!"...thankfully, Sulik cut him off at the door, while I introduced him to the Desert Eagle I picked up from Tyler) and killed him before he could get off-screen. That may have been random, but I'd imagine that's why someone can't get that quest to end right. Seeing as that guy also carries a Desert Eagle and has decent HP, I dunno, maybe he should fight as well? Don't know if him running is intentional or not though.
Besides that, the Den feels far more fleshed out now, did the Orphanage quest without a hitch, and Anne's Diary is a nice hint (though I imagine someone playing through this release doesn't likely need it, of course), the only thing I've found so far that doesn't seem to be working is the well at the Primitive Tribe. It says it's missing a bucket and rope, both of which I have, but using them on it, or repairing, or anything else I try, doesn't seem to have any effect. Might be nothing, just giving whatever feedback I can though.
Again, excellent job, I've been following the news on this a hell of a lot more than I have Fallout 3 to be honest, and it doesn't disappoint in the least, thank you.