Minigun Jim
It Wandered In From the Wastes
And placing the pipe rifle in the desk outside, so people with low lock picking skill don't lose out on it.
There's a couple of easy ways around that if you get creative (one of the reasons I love Fallout)
<spoiler>Get the "town greeter" by the billboard drunk. Steal his Molotov Cocktail. Throw it at the door to destroy it.
Find a Sledgehammer in Klamath (Sulik has one, there's another in the Rat Caves). Smash the door down by attacking it with the hammer.</spoiler>