I've had a few problems with 2.33, mostly in vault 23... anyway:
1: When talking to your aunt after completing the Temple of trials; she says to you: "So you've returned. Did you find the holy 13?" and your only possible reply is: "Then get yourself out of here and find it! People are depending on you!".... Seems like that's what she should say after you say "no" or something.
2: The quest with the guy in the Vault city fence jail has a lot of "error" things in it. Like when looking at the prisoner, or when talking to Steve the only dialogue option that isn't "error" is the one asking Steve if he loves money.
Also when you free the "error" prisoner and talk to him at his brother's tent, he says "I don't even know how to express my thanks", and his green text "thank you" at the same time. There's also some problems with the guards telling you not to touch the fence before they move away, and if you do certain things the gate will remain open permanently.
3: "Old Joe the local idiot savant"(Aka: Ian) in Vault city suffers from the same glitch as the wild man in the primitive tribe. He appears "dead" when you look at him.
4: Also some other small stuff like getting a "Monks" status log in my pip boy, even though I never did anything with any monks". There was also one time a encounter full of roaches was mislabeled as a caravan encounter, and of course the roaches were using the wasp model for some reason; but that's a known problem.
5, Vault 23:
Let's see ...
5.1:Car disappears when going to the map
5.2:Some combat glitches.(I killed the last rat on level 2, but my party members thought it was still alive and shot at nothing. Then when I finally was able to end combat, my party members did their attacking animations for a second while the chosen one did the dodging animation.)
5.3: When reloading a save from inside the vault it would always say I found vault 13, supposedly give me 2000EXP and I'd hear the level up sound.
5.4: The holo-disk/voice encrypted door you find on one of the bodies is seriously screwed up. When you activate it , it brings up a dialogue box, asking you for a password... none of the options are correct, and it's impossible to exit the dialogue box/inventory merged screens, so you have to quit the game.
5.5: Every time you leave the humongous rat's lair and go back to level 3 you get that vault 13 message, and you actually get 2000EXP points.
5.6: After killing the rat, even things that used to work will be replaced by "error", which includes the guy that gives you the key to the vault, and the level 1 computer.
6: This might happen in the vanilla game too, but I'm not sure. After killing Westin, if you negotiate a higher price for accepting the Carson mission, or even ask about Carson, the dialogue box will just freeze on the screen at the end of the conversation. Then, even if you manage to blindly select one of your Party members and talk to them, and fix your screen... Bishop will act like you had rejected to do the job, and asks again(causing the dialog box freeze again). It only works correctly if you accept the job right away, ask no questions, and end it with "I understand".