Not sure if it's been brought up yet, and if it has, sorry, but can we please discuss Super Mutants as a huge plot hole in this game?
First of all, the Institute is basically the Enclave 2.0, except even more stupid and hypocritical. When the Enclave ran FEV experiments, they at least had some good results, such as Frank Horrigan and Intelligent Deathclaws. And they pretty much stopped when they saw what FEV did to people considering they're all about the "purification of humanity". Apparently the Institute are far more stupid than that, since every single Super Mutant in Boston came from them.
The Enclave at least had the common sense to stop when they realized FEV was extremely dangerous, but I guess the Institute thought "Oh, it turns people into brainless giant green monsters that want to destroy humanity..? Better make more of them! Lots more of them!" Considering Super Mutants are sterile and always have been, even the originals made by the Master himself, that means the Institute created a literal army of these monsters only to release them on the Commonwealth for no reason at all.
Like, what the fuck? Why? Why not just destroy the Super Mutants you created? They mention multiple times that hardly any of them have ever gone up on the surface because of radiation and that they want to make the surface a better place, yet they sent a massive armada of giant green men to kill everyone? What was the point!