I'm sure many who were paying attention to the pre-release hype for Fallout 4 remember what happened when the news leaked that your character's son was going to be one of the big names among the factions playing at controlling the Commonwealth. Fans who thought this was a huge spoiler went crazy, the joke about how to kill your son went viral, and then we had Pete Hines enter the fray with a statement that regardless of this reveal, players would have more than enough to like about Fallout 4.
Sorry Pete. That's a lie if I ever heard one.
In essence, what he's admitting to here is this part of the main plot, the part that pulls your character into and through the world of Fallout 4, is completely forgettable and not as big a deal spoiled as it would've been unspoiled.
Here's a comparative example, just to show how dumb this is: Let's say Fallout 1 had the same caliber of hype surrounding it that Fallout 4 had, and then some players got their hands into the core of the game early, found out about how the main plot ends, and then posted things like, "Hey, don't ask the water merchants to supply your vault. You'll lose more easily that way." And then let's say Tim Cain (Sorry, Tim) came forward and said, "I'm sorry this got spoiled for you, but it's just one option in our game. You can try it if you choose, though."
See how dumb this gets? Finding the water chip is the crux of the early game in Fallout 1, and you're on a timer, so of course the water merchants making trips to extend your time seems like a great idea, but being told that choice is not that bad spoiled versus unspoiled is a blatant lie because it changes the outcome of events in the game in a big way.
All that said, I was laughing all the way to the bank at the reveal for Fallout 4. I was under the impression that your character would be turned synth while under then given false memories before being let loose, you know something very sci-fi and in line with the film the developers thought so highly of when designing this game.
Of course, the main plot of finding your character's son is terrible in many other ways. For one, it's something that leaves a segment of players, likely a large one, open to simply not care about it and abandon it in favor of wandering the wastes. A major sin for RPG storytelling on par with giving your character the wrong emphasis for stopping the Darkspawn in Dragon Age: Origins. And if the Main Quest is forgettable, what does that say about the rest of the game?
Now, full disclosure here: I have not played the DLCs, nor do I ever plan to. I've seen plenty of them thanks to past roommates and other players to know that the 49.99 I would be spending to get those DLCs would be better spent on other games, or new PC hardware. What I have to say is strictly on the core game, but, again, if the core story is bad, what should that say about the rest of the game? If the DLCs are where the good stuff is, the game itself is even worse, but if the DLCs are mediocre, then it's a waste of money again.
In brief, what Bethesda was trying to do with Fallout 4 was ape New Vegas. They gave four main factions vying for the Commonwealth (The Institute, The Railroad, The Brotherhood of Steel and The Minutemen) just as you had four factions vying for New Vegas (Caesar's Legion, The NCR, Mr. House, and Yes Man (Independent)), but they failed to grasp why your choices in New Vegas had such an impact.
Because the characters and world on display supported the desire of these factions to control such an important area of the West Coast, which in turn made you think about what direction you wanted to take the story, and because the West Coast area of California and Nevada has been part of Fallout canon since 1997. New Vegas drew from the isometric games to help build the world. Fallout 4 builds on whatever Bethesda felt was enough to use from Fallout 3. (Dr. Li and several other faces return from Fallout 3, in fact.)
What makes this even worse is the fact that there are only two endings in the game: One for if you sided with The Institute, and the other for if you did not. You're also shown no slides detailing choices you made throughout the game, because there are no decisions you can make, or things you can affect, on a scale even comparable to The Necropolis, Vault City, New Vegas, or any other games from Black Isle/Obsidian. That or Bethesda simply left the idea on the cutting room floor like other things I'll get to shortly.
It really makes one appreciate the slides you earned by finishing New Vegas and Skies of Arcadia. (Yeah, that game had ending slides, and they're still awesome to this day.)